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Depression can be caused by diet, stress, or just about any other reason that you can think of but if you are depressed without an explanation as to why then you should see a professional. This type of depression with time will subside and you will improve but it is the type of depression that is brought on for no reason that is concerning. duloxetine without prescription Cymbalta is an anti-depressant that is used to treat severe depression as well as anxiety. Depression can be brought on by a recent event such as a loss of a job or a death of a loved one but in this case it is normal to feel depressed.